IOMAI IMMUNITY THAT'S MORE THAN SKIN DEEP
Transcutaneous delivery and thermostability of a dry trivalent inactivated influenza vaccine patch
Influenza and Other Respiratory Diseases (Online March 27, 2008)
Doi: 10.1111/j.1750-2659.2008.00040.x

Transcutaneous immunization with heat-labile enterotoxin: development of a needle-free vaccine patch
Expert Rev Vaccines 2007;6(5):809-819.

The adjuvant patch: a universal dose sparing approach for pandemic and conventional vaccines.

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 BioPharm Intl: Guide to Vaccine Development and Manufacture 2007; (Suppl Aug):34-45.

Transcutaneous immunization with the heat-labile toxin (LT) of enterotoxigenic Escherichia coli (ETEC): protective efficacy in a double-blind, placebo-controlled challenge study.

                  Vaccine 2007; 25(18):3684-3691


Safety and immunogenicity of an ETEC vaccine patch containing heat-labile toxin: use of skin pretreatment to disrupt the stratum corneum.

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Mass vaccination: solutions in the skin.

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GM-1 binding deficient exotoxin is a potent non-inflammatory broad-spectrum intradermal immunoadjuvant.

 J Immunol 2006;177(2):1197-1207.  

Transcutaneous immunization using the heat-labile enterotoxin E. coli as an adjuvant.

 In: Schijns VE and O'Hagan D (Eds.), Immunopotentiators in Modern Vaccines, Elsevier Scientific Ltd., United Kingdom, pp. 253-273, 2006.

Transcutaneous immunization: antigen and adjuvant delivery to the skin.

 In: Bronaugh RL. and Maibach HI. (Eds.), Percutaneous Absorption: Drugs, Cosmetics, Mechanisms, Methods, 4th Edition, Marcel Dekker Inc., New York, NY, 2005. 

Improved immune responses to influenza vaccination in the elderly using an immunostimulant patch.

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Immunization using the skin: new approaches.

 In: Moingeon P (Ed.), Vaccines: Frontiers in Design and Development, Horizon Scientific Press, Ltd., Wymondham, UK, pp. 81-104, 2005.

Dose sparing for influenza vaccination using intradermal immunization.

 N Engl J Med 2004;351(22):2295-2301.

Induction of protective immunity against lethal anthrax challenge with a patch.

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Immunostimulant patch enhances immunity to influenza vaccine in aged mice.

 J Virol 2004;78(14):7610-7618.

Transcutaneous immunization induces CTLs and protective immunity by migration of primed skin dendritic cells.

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Needle-free skin patch vaccination method for anthrax.

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Adjuvants for the future.

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Transcutaneous immunization.

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Transcutaneous immunization and immunostimulant strategies.

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Immunostimulant patch containing heat labile enterotoxin from E. coli enhances immune responses to injected influenza vaccine through activation of skin dendritic cells.

 J Virol 2003;77(9):5218-5225.

Transcutaneous immunization and immunostimulant strategies: capitalizing on the immunocompetence of the skin.

 Expert Rev Vaccines 2003;2(2):253-267.

Survey of human-use adjuvants.

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Transcutaneous immunization.

 In: Dietrich G and Goebel W (Eds.), Vaccine Delivery Strategies, Horizon Scientific Press, Wymondham, UK, pp. 53-81, 2002.

Safety and immunogenicity of a prototype enterotoxigenic Escherichia coli vaccine administered trans

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  Infect Immun 2002;70(4):1874-1880. Copyright: © 2002, American Society for Microbiology. All rights reserved.

Transcutaneous immunization using colonization factor and heat labile enterotoxin induces correlates

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  Infect Immun 2002;70(3):1056-1068. Copyright: © 2002, American Society for Microbiology. All rights reserved.

Transcutaneous immunization: an emerging route of immunization and potent immunostimulation strategy.

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Transcutaneous immunization.

 In: Ellis R (Ed.), New Vaccine Technologies, Landes Bioscience & Eurekah.com, Georgetown, TX, pp. 292-304, 2001.

Transcutaneous immunization: T cell responses and boosting of existing immunity.

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Transcutaneous immunization with bacterial ADP-ribosylating exotoxins, subunits, and unrelated adjuvants.

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Transcutaneous immunization of domestic animals: opportunities and challenges.

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Transcutaneous immunization: a human vaccine delivery strategy using a patch.

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Transcutaneous immunization: a new vaccine delivery strategy.

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Transcutaneous immunization.

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Advances in vaccine delivery: transcutaneous immunization.

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  Opin Investig Drugs 1999;8(6):797-805. Copyright: © 1999, Ashley Publications. All rights reserved.

Principles of transcutaneous immunization using cholera toxin as an adjuvant.

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Transcutaneous immunization with bacterial ADP-ribosylating exotoxins as antigens and adjuvants.

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  Infect Immun 1999;67(3):1100-1106. Copyright: © 1999, American Society for Microbiology. All rights reserved.

Transcutaneous immunization with cholera toxin protects mice against lethal mucosal toxin challenge.

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  J Immunol 1998;161(7):3211-3214. Copyright: © 1998, American Association of Immunologists. All rights reserved.

Skin immunization made possible by cholera toxin.

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  Nature 1998; 391(6670):851. Copyright: © 1998, Nature America, Inc. All rights reserved.

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